Fosamax
Fosamax (known generically as Alendronate) is prescribed to increase bone density and treat osteoporosis. Fosamax is in a class of drugs known as bisphosphonates. Bisphosphonates such as Fosamax are also used intravenously to treat cancer patients. However, Fosamax and other bisphosphonates have now been linked to osteonecrosis of the jawbone (ONJ).Since 2001 there have been more than 2,400 reported cases of ONJ in patients who took bisphosphonates like Fosamax. Most of these reports occurred in patients who took the drugs intravenously. There have also been reports of patients taking bisphosphonates in pill form suffering side effects such as bone, joint, or muscle pain, causing some patients to require mechanical aid to move around.
The link between ONJ and bisphosphonates was published in the Journal of Oral and Maxillofacial Surgeons.ONJ is a disease that causes bone tissue in the jaw to not heal after minor trauma such as a dental extraction. Any trauma that causes the bone to become exposed can result in fractures and infections. Symptoms of ONJ include irregular sores, pain or swelling in the jaw, infection and altered sensation (numbness or a heavy feeling in the jaw).
ONJ causes serious infections, swelling, and loosening of the teeth. Patients with ONJ report a great deal of pain when eating or talking. In many cases long-term antibiotic therapy or surgery to remove dying bone tissue are required as treatment.
Recently, lawsuits have been filed against Merck, the maker of Fosamax, claiming that the company knew about the side effects but failed to warn consumers.
If you are taking Fosamax and require dental extractions that cannot be delayed, speak to your doctor immediately about your options.
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